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Contact Information:
Ekaterina M. Nestorovich
Research Fellow
Section on Molecular Transport
Laboratory of Physical and Structural Biology
NICHD, National Institutes of Health
Bld.9, Room 1E-106
Bethesda, MD 20892-0924
Telephone: (301) 402-4702
Email: nestoroe@mail.nih.gov |
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Research Experience
With a background in physical chemistry and electrochemistry most of my previous research focused on mechanisms of charge transfer processes at metal electrodes and the double layer structural effects in the kinetics of electrode reactions as well as on fundamental and analytical electrochemistry of metal complexes solutions.
Current Research Interests
My research interest is biophysics of ion channels in bilayer lipid membranes with an emphasis in the channel-facilitated transport of metabolites and other large solutes across the membranes. Membrane proteins respond to their immediate environment, such as, for example, surrounding lipids and local acidity. Therefore, to study channel under precisely controlled conditions, we reconstitute channel-forming proteins into planar lipid bilayers. In my studies I focus on channel formed by OmpF (outer membrane protein F) from the outer membrane of E.coli; OprF from the outer membrane of Pseudomonas aeruginosa; PA63 (anthrax protective antigen).
Current Projects:
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