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Present Position and Address
Senior Investigator, Section Chief
Section on Molecular Transport
Laboratory of Physical and Structural Biology
NICHD, National Institutes of Health
Bld.9, Room 1N-124B
Bethesda, MD 20892-0924
Telephone:
(301) 402-4701
Fax: (301) 496-2172
Email:
bezrukos@mail.nih.gov
Honors and Awards
| 1973 |
M.S. Summa cum laude, St. Petersburg Polytechnic University |
| 1979 - 1990 |
Russian Academy of Sciences grant: Fluctuation Phenomena in Ionic Systems |
| 1981 - 1991 |
Member of the Russian Academy of Sciences Council "Biological Membranes" |
| 1986, 1989, 2004 |
"Best Research Project" Award, St. Petersburg Nuclear Physics Institute |
| 1986 |
"Most Important Scientific Contribution" Award at the All-Union Conference on Noise in Physical Systems, Puschino, Russia |
| 1989 |
"Most Important Scientific Contribution" Award at the All-Union Conference on Noise in Physical Systems, Palanga, Lithuania |
| 1999 |
"Best Research Project" Award (First Prize), St. Petersburg Nuclear Physics Institute |
| 2002 - 2003 |
Elected Member of Executive Council of the Division of Biological Physics of the American Physical Society |
Education
| Institution |
Address |
Degree, Year |
| St. Petersburg Polytechnic University |
St. Petersburg (Leningrad), Russia |
M.S. (with highest distinction) Electronics, Theoretical Physics, 1973 |
| Moscow State University |
Moscow, Russia |
Ph.D., Physics and Mathematics, 1981 |
Academic and Activities
Positions Held:
| 1973 - 1975 |
Research Student, St.Petersburg (Leningrad) Nuclear Physics Institute |
| 1975 - 1981 |
Assistant Research Scientist, St.Petersburg Nuclear Physics Institute, Laboratory of Condensed Matter Physics |
| 1981 - 1987 |
Research Scientist, St.Petersburg Nuclear Physics Institute, Laboratory of Condensed Matter Physics |
| 1987 - 1990 |
Senior Research Scientist, St.Petersburg Nuclear Physics Institute, Laboratory of Condensed Matter Physics |
| 1990 - 1992 |
Visiting Research Associate, University of Maryland |
| 1990 - 1992 |
Special Volunteer, National Institutes of Health, LBM, NIDDK |
| 1992 - 1998 |
Visiting Scientist, National Institutes of Health, LSB, DCRT and LPSB, NICHD |
| 1998 - 2002 |
Investigator, Head of Unit, National Institutes of Health, LPSB, NICHD |
| 2002 - present |
Senior Investigator, Section Chief, National Institutes of Health, LPSB, NICHD |
| 1975 - 1976 |
Lecture Course: "Non-Equilibrium Thermodynamics", St. Petersburg Nuclear Physics Institute |
| 1978 |
Lecture Course: "Non-Equilibrium Thermodynamics", St.Petersburg Polytechnic University |
Mentoring Experience:
5 post-doctoral researches, 2 graduate students, 2 NIH summer students
Scientific Reviewing:
| Journals: |
Nature, Science, Physical Review Letters, Biophysical Journal, Physical Review E, Physics Letters A, Europhysics Letters, Journal of Membrane Biology, European Journal of Physiology, Journal of Theoretical Biology, Biochimica et Biophysica Acta, Modeling in Biology, Journal of Physical Chemistry, Journal of Applied Physics, Chaos, etc. |
Grant agencies: |
NIH, NSF, Office of Naval Research, Petroleum Research Fund, Louisiana Board of Regents, Israel and Czech national science foundations |
Organization of Conferences and Meetings
| 1999 |
Co-organizer (together with V.A. Parsegian), NIH Workshop "Electrostatics in Ion Channels" |
| 2001 |
Co-organizer (together with D.W. Deamer), NIH Workshop "Polymers in Nanoscopic Pores: Applications to Single Molecule Analysis and Metabolite Transport" |
| 2002 |
Organizer, Symposium "The Physics of Single Molecules: Nanopore Approaches" at the Annual American Physical Society meeting, Indianapolis |
| 2002 |
Chair, 3-rd International Conference "Unsolved Problems of Noise and Fluctuations", Washington, D.C. |
| 2003 |
Chair, 1-st International Conference "Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems," Santa Fe |
| 2004 |
Co-Chair, 2-nd International Conference "Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems," Gran Canaria, Spain |
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| Other Scholarly Activities |
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| 1986 - 1993 |
Member of the St. Petersburg Nuclear Physics Institute Council "Condensed Matter Physics" |
| 1987 - 1990 |
Editor of the St. Petersburg Nuclear Physics Institute Periodical "Condensed Matter Physics" |
| 1995 - 1999 |
Member of the Advisory Committee, 1-st and 2-nd International Conferences "Unsolved Problems of Noise and Fluctuations" |
| 1998 - 1999 |
Member of the International Scientific Committee of Marian Smoluchowski Symposium on Statistical Physics |
| 2000 - 2001 |
Member of the Scientific Program Committee, International Conference Series "Noise in Physical Systems and 1/f Fluctuations" |
| 2000 - 2003 |
Member of the Executive Council of the Division of Biological Physics of the American Physical Society |
| 2000 - present |
Executive Editor (biological and biomedical systems, International Interdisciplinary Journal "Fluctuation and Noise Letters" |
| 2001 - present |
National Research Council Adviser |
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| Recent Invited Talks Outside NIH |
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| 2001 |
- "Learning from 'noise': From vacuum tubes to proteins to malaria", The National Academies, Solid State Sciences Committee meeting, Washington, D.C.
- "Voltage-dependent ion channels as transducers of small sensory signals", American Physical Society meeting, Seattle
- "Under- kT signals' in sensory biology", Workshop on Physics of Information and Synchronization in Stochastic Dynamics, Dresden, Germany
- "From physics of fluctuations to malaria: Noise research in biology", 16-th International Conference "Noise in Physical Systems and 1/f Fluctuations", Gainesville
- "Ion channels, negative resistance, and sensory signals", 14-th Marian Smoluchowski Symposium on Statistical Physics, Zakopane, Poland-"Voltage-dependent ion channels as active elements of signal amplifiers", Mini-Symposium on Electroreception, University of Missouri, St. Louis |
| 2002 |
- "Counting single molecules going through membrane channels", University of San Francisco
- "Hierarchy of fluctuations in large channels of biological membranes", Harvard University
- "Ion channels as molecular Coulter counters", International Conference "Membrane Bio-Electrochemistry: From Basic Principles to Human Health", Moscow, Russia
- "Thermodynamics and kinetics of polymer partitioning into nanopores of biological channels", Gordon Research Conference on Polymer Physics, Salve Regina University
- "Using ion channels to count single molecules", Cornell University |
| 2003 |
- "Stochastic resonance as a consequence of improved statistics", University of Maryland, College Park
- "Quantum computing and information processing in biology", SPIE 1-st International Symposium on Fluctuations and Noise, Santa Fe, NM
- "Noise analysis in studies of protein dynamics and molecular transport", International Conference on Noise and Fluctuations, Prague, Czech Republic
- "Sensing Nature's signals: Ion channels as active elements of linear amplification", Ohio University, Athens
- "Noise analysis in biophysics: From vacuum tubes to proteins, antibiotics, and human health", Texas A&M University |
| 2004 |
-"Information and noise in ion channel signals", Winter Symposium on Physics of Quantum Electronics, Snowbird, UT
-"Linear amplification by a non-linear system: Ion channels, negative resistance, noise and stability", Workshop on Complex Dynamical Processes in Electroreceptors and Hair Cells, Dresden, Germany
-"Voltage-induced 'gating' of bacterial porins as reversible protein denaturation", SPIE 2-nd International Symposium on Fluctuations and Noise, Gran Canaria, Spain |
Book Editing
| 1. |
Unsolved Problems of Noise, S.M. Bezrukov, editor, American Institure of Physics, AIP Conference Proceedings, vol. 665, 2003 (621 pp) |
| 2. |
Fluctuation and Noise in Biological, Biophysical, and Biomedical Systems, S.M. Bezrukove, H. Frauenfelder, F. Moss, editors, Proc. SPIE, vol. 5110, 2003 (356 pp) |
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